Mark Lyles MD Obituary
With solemn hearts, we announce the passing of Mark Lyles MD of Charleston, South Carolina, whose presence will be deeply missed, having departed on August 13, 2025 at the age of 58. Family and friends are welcome to leave their condolences on this memorial page and share them with the family.
He was predeceased by: his sister Heather Lyles. He is survived by: his parents, Daniel Ashton Lyles and Dorothy Mathis Lyles; his children, Samuel Finn Lyles of Mount Pleasant and Georgia Claire Lyles of Mount Pleasant; his former wife Robin Young Lyles of Mount Pleasant; his siblings, Paige Lyles Stokes (Danny) of Sumter and Charles "Chuck" Van Patten of Lexington; and his nieces and nephews, Amber McGarity (Colin), Mary Daniel Griffith (Austin), Todd Brown (Gaffney) and Luke Stokes (Ansley).
In lieu of flowers, his family invites you to honor his memory by contributing to the Dr. Mark Lyles Medical Mission Scholarship Fund through OneWorld Health.

August 28, 2025
Brian Zeno lit a candle